Fish oil may protect against diseases like Parkinson’s

Parkinson’s disease is a neurodegenerative disorder first described by James Parkinson in 1817 as ‘paralysis agitans’ (shaking palsy). Dr Nicholas Bazan and colleagues from Louisiana State University Health Sciences Center recently presented new research findings to the American Society for Nutrition at the annual meeting for Experimental Biology 2009. These findings demonstrate that omega-3 fatty acids in the diet may help prevent the misfolding of a protein resulting from a gene mutation, which is a characteristic of neurodegenerative diseases like Parkinson’s and Huntington’s.

Dr Bazan and colleagues developed a cell model with an Ataxin-1 gene mutation, caused by an abnormally high number of base repeats (cytosine, adenine and guanine), which induces the production of misfolded proteins. Consequently, these proteins acquire toxic gains-of-function and become averse to degradation by the ubiquitin-proteasome system (UPS) which serves to dispose of aberrant proteins. One resultant disorder of this Ataxin-1 mutation is Spinocerebellar Ataxia (SCA) characterised by lack of muscle coordination, speech impairment, deformity of the spine, irregularity of movement along with other developing symptoms.

The research led by Dr Bazan, who is the Director of the Neuroscience Center of Excellence found that docosahexaenoic acid (DHA), an essential omega-3 fatty acid, protects the cells from the Ataxin-1 mutation defect. DHA is obtained from the diet is derived mainly from marine alage and fish oils. It is known to be the most abundant omega-3 fatty acid found in the membrane phospholipids of neurons. Functionally, free DHA produces neuroprotection D1 (NDP1) which limits oxidative-stress induced cell death. NDP1 is an effective anti-inflammatory signalling molecule with neuroprotective value in several neurodegenerative diseases. DHA is required to maintain membrane integrity and subsequently NDP1 protects cells from apoptosis.

Therapeutically, this research by Dr Bazan and colleagues provides proof of principle that NDP1 can be utilised to target neurodegenerative diseases. Dr Bazan is quoted as saying that the results of his study should provide the basis of new therapeutic approaches to manipulate retinal pigment epithelial cells to be used as a source of NDP1 to treat patients with disorders characterised by this mutation like Parkinson’s, Retinis Pigmentosa and some forms of Alzheimer’s Disease.

Article submitted thanks to Reading Scientific Services Ltd     Read More


Colloidal silver, natural anti-biotics

I hate anti-biotics and all that they do to our bodies. Sometimes there seems little alternative. However, colloidal silver is certainly worth considering for this use. What is colloidal silver and what is it useful for?

A colloid is an incredibly small particle of matter, small enough to pass through the membranes in our bodies and into our system.

Colloidal silver supports the natural defence systems of the body and has been known as a remarkably effective natural antibiotic for centuries.It is very alkaline and has a slight magnetic charge, resulting from the way it is produced, both of which make it more effective in how it benefits us. If you are more scientific than I am you may appreciate that the colloidal silver works by acting as a catalyst, disabling the enzyme that the bugs, bacteria and fungi need to breathe, so the invaders are suffocated but no harm is done to our bodies.

There is much modern research which has endorsed the conclusions that colloidal silver can even help eradicate antibiotic-resistant microbes like MRSA , the Avian Influenza (bird flu), and Human Corona virus (SARS).

In the mid-1970s, Dr. Robert O. Becker at Syracuse Medical University began his research into colloidal silver. He concluded that the research established the fact that silver kills bacteria, something that has been known for centuries. Silver’s innate anti-microbial effect was actually common knowledge among doctors around 60 years before Becker’s time. In fact, in the early 1900’s Alfred Searle, founder of the global Searle Pharmaceutical Company, had already discovered that silver in its liquid colloidal form could kill even the most deadly of pathogens. In his book Colloids in Biology and Medicine, 1919, Searle wrote:

“Applying colloidal silver to human subjects has been done in a large number of cases with astonishingly successful results. Colloidal silver has the advantage of being rapidly fatal to microbes without toxic action on its host. It is quite stable.”

Unlike prescription antibiotic drugs, silver does not create resistance or immunity in pathogens killed by it.

Just how effective is colloidal silver?

Several new studies have demonstrated the fact that silver is one of the most effective agents in the battle against deadly or extremely harmful antibiotic-resistant super bugs. One was the Brigham-Young Clinical Study which concluded that a number of the antibiotic drugs which had previously been able to kill MDR (multiple drug-resistant) pathogens such as MRSA could be restored to full efficacy against the deadly pathogens, but only if colloidal silver was used in conjunction with the drug. In an Iranian Clinical Study it was also found that silver increases the effectiveness of antibiotic drugs against infections. A Taiwanese study published as recently as 2007 concluded that colloidal silver, by itself, was highly effective in eradicating some super bugs including MRSA.

These studies were high powered and were testing against the big boys of the bug world, but for you and me on a daily basis, how should we be aware of the benefits of colloidal silver? It is worth a try for minor bugs too. The trials show it to be effective in helping to combat acne, strengthen against allergies, arthritis, athletes foot, boils, burns, candida, cystitis, diabetes, eczema, hay fever, indigestion, parasitic infections, psoriasis, ringworm, warts and yeast infections. That is quite a list, but don’t go too mad, and read more widely about it before you purchase because overdoing contact with silver can make you go a little grey before your time.

Colloidal silver can be taken by mouth by either placing droplets under your tongue for quick absorption or put into water and drink. Alternatively you can apply the colloidal silver directly onto cuts, burns, skin infections or acne. Just make sure you have true colloidal silver (it is slightly cloudy, never totally clear). Colloidal silver is available from Higher Nature in both 100ml or 15ml spray for the throat or spraying under your tongue for quick absorption. Do not exceed the stated dose.